Cryogenic electron microscopy system with 300 kV transmission cryo-electron microscope and cryogenic focused ion beam scanning electron microscope
Buyer: Helsingin yliopisto
- Published
- 19 December 2025
- Estimated value
- €5,720,000
- Place of performance
- FI1B1
- Procedure
- Open procedure
- Lots
- 1
- Notice number
- 00849454-2025
- Reference
- 5894f967-7322-4e55-bfb2-13627e802a51
- Official source
- Official source
CPV codes
- 38510000Microscopios
Description
The Institute of Biotechnology Structural Biology Platform (INSTRUCT-HiLFE) will be upgrading its cryogenic electron microscopy (cryo-EM) services. The current 200 kV transmission electron microscope will be replaced with equipment offering higher resolution for both single-particle and tomography analysis. To enable this, we will establish an integrated workflow for producing samples for tomography and single-particle analysis. Specifically, we will acquire a 300 kV cryogenic transmission electron microscope (cryo-TEM) suitable for high-resolution structural biology, together with a software and hardware compatible cryogenic focused ion beam scanning electron microscope (cryo-FIBSEM) for lamella sample preparation required in high-resolution tomography. The instruments will be installed at the Institute of Biotechnology, University of Helsinki (UH). Delivery and installation will take place in 2027.
Award criteria
- Price — The total price must be indicated as a fixed net price excluding VAT (in EUR, VAT 0 %, maximum 5 720 000 euros). The total price must include delivery costs, insurance costs, installation of the…
- Quality — Highest number of tomography-based structures obtained using the cryo-TEM instrument or its predecessor at better than 5 Å (0.143 FCS) resolution deposited in EMDB.
- Quality — Cryo-TEM can be loaded with 10 or more samples at one go.
- Quality — Cryo-TEM can hold samples at temperature of 90 K or lower inside the microscope.
- Quality — Sustainability: The current Falcon 4i detector can be installed on the new microscope by the supplier.
- Cost — Service contract at fixed price (full service, including unlimited work and parts, and remote support) for an additional four years for both instruments, lowest price .
- Quality — Maximum Cryo-FIBSEM cryo-stage movement range on the x and y axes (x, y range) (largest stage area available.
- Quality — Documented use of provider cryo-FIBSEM instrument in tomography applications in at least three peer-reviewed scientific publications with structures reporting resolution better than 8 Å (0.143 FCS).
- Quality — 360 degree rotation of the cryo-FIBSEM cryo-stage should be fully continuous in both directions.
- Quality — The delivered microscopes come without third-party components.
- Quality — Number of years of extended warranty beyond 1 year provided
- Quality — The warranty and extended warranty include automated software to check on daily basis the status of the microscope, a regional customer manager and portal/online access for operational parameters to…
Awards
| Awarded to | Amount | Date |
|---|---|---|
| Thermo Fisher Scientific- FEI Europe BV. Branch Denmark | €6,664,836 | — |
Official publications
- TED · 00849454-2025 · 19 December 2025
- OJS · 245/2025 · 19 December 2025
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Frequently asked questions
- What is the estimated value of this tender?
- The estimated value published by the buyer is €5,720,000.
- Who is the buyer of this tender?
- The contracting authority is Helsingin yliopisto (European Union).
- How can I bid for public tenders in European Union?
- Bids are submitted through the official procurement portal of European Union. El Vínculo helps you find tenders and analyse their documents; submission always happens at the official source.
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