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Awarded United Kingdom Services

Onasemnogene Abeparvovec Intravenous (Zolgensma®) Service & Onasemnogene Abeparvovec Intrathecal (OAV101 IT) Service

Buyer: NHS England

Published
22 September 2026
Estimated value
£26,143,000
Place of performance
UK
Procedure
Open procedure
Notice number
089823-2026
Reference
ocds-h6vhtk-06ae08
Official source
Official source

CPV codes

Description

Intention to award the Onasemnogene Abeparvovec Intravenous (Zolgensma®) Service & Onasemnogene Abeparvovec Intrathecal (OAV101 IT) Service. This is a a one-time, in vivo gene replacement therapy, for use in babies aged 12 months and under, that utilises an adeno-associated virus serotype 9 (AAV9) vector, modified to contain a functional copy of the human SMN1 gene. It is administered intravenously, allowing the vector to deliver the gene into motor neurones and peripheral tissues, enabling the sustained expression of survival motor neuron (SMN) protein, which is deficient or mutated in individuals with SMA. Onasemnogene abeparvovec intrathecal (OAV101 IT) is a one-time in vivo gene replacement therapy for patients with SMA, proposed to treat individuals with SMA aged 2 years and over. This intrathecal injection will be used to treat a distinct cohort of SMA patients to Zolgensma. It will be assessed via NICE’s technology appraisal programme, with an expected final guidance publication date in late 2026. Procurement was carried out in Lots for the services as detailed above. Contract values are estimated and will be dependent on number of patients actually treated at each awarde…

Lots (3)

LotDescriptionCPV codeAmount
1 Lot 1
UK
85100000 Health services —
2 Lot 2
UK
85100000 Health services —
3 Lot 3
UK
85100000 Health services —

Awards

Official publications

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Frequently asked questions

What is the estimated value of this tender?
The estimated value published by the buyer is £26,143,000.
Who is the buyer of this tender?
The contracting authority is NHS England (United Kingdom).
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Data collected from official public procurement sources. Amounts as published by the buyer.