Multiphoton imaging system
Buyer: Karolinska Institutet
- Published
- 10 December 2024
- Procedure
- Negotiated procedure
- Lots
- 1
- Notice number
- 00754171-2024
- Reference
- 829cdc2e-e836-42d5-93d7-0ec14c7cfdb0
- Official source
- Official source
CPV codes
- 38510000Microscopios
- 38515200Microscopios de fluorescencia
Description
The research group of Stefanos Stagkourakis will carry out a project focused on all-optical investigations that provide the capability of imaging and manipulating neuronal activity at the same time. Specifically, multiphoton imaging of Ca2+ and voltage indicators will be used to study neuron activity on large neuron populations in vivo and in vitro. Successful pursuit of this work requires simultaneous recording of activity and manipulation through multiphoton photostimulation of pre-selected neuron ensembles to study a causal role of specific neuron subpopulations in behavior. A key component of the project is complementing the head-fixed in vivo neural activity and ensemble manipulation recordings with neuron activity imaging in freely moving animals through the Inscopix miniscope technology. In order to be able to carry out the research, KI needs to purchase an Multiphoton imaging system that meets the following requirements: a. The system must have a volumetric imaging solution which is decoupled from the photostimulation pathway while still offering a travel range that will allow imaging between planes of interest that are spatially separated by at least 390um in Z. This is …
Awards
| Awarded to | Amount | Date |
|---|---|---|
| BRUKER France SAS - Division BioSpin | €700,000 | — |
Official publications
- TED · 00754171-2024 · 10 December 2024
- OJS · 240/2024 · 10 December 2024
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