In Vivo Validation
Buyer: Plectonic LOGIBODY GmbH
- Published
- 4 March 2024
- Place of performance
- DED51
- Procedure
- Negotiated procedure
- Documents
- 1
- Notice number
- 00131805-2024
- Reference
- 748c4776-5d4b-48db-a734-60f0fd6daa6c
- Official source
- Official source
CPV codes
- 73000000Servicios de investigación y desarrollo y servicios de consultoría conexos
Description
Plectonic is searching for a service provider covering multiple murine in vivo studies for T-cell engagers (focusing on anti-CD3 T-cell engagers with binding to a selection of differential tumor antigens) currently in discovery / early preclinical phase. The work packages will cover the conduction of several animal experiments typically required for characterization of T-cell engagers and biologicals to evaluate anti-tumor efficacy, pharmacokinetic parameters, generate proof-of-concept data and identify lead candidates including data-driven selection of most suitable tumor antigen combinations and indication. Reference molecules for these types of workpackes are among others blinatumomab (CD19xCD3), glofitamab (CD20xCD3), AMV564 (CD33xCD3) or solitomab (EpCAMxCD3).
Lots (3)
| Lot | Description | CPV code | Amount |
|---|---|---|---|
| 1 | Efficacy studies | 73000000 Servicios de investigación y desarrollo y servicios de consultoría conexos | — |
| 2 | Pharmacokinetic, biodistribution and tumor penetration experiments | 73000000 Servicios de investigación y desarrollo y servicios de consultoría conexos | — |
| 3 | Immunogenicity | 73000000 Servicios de investigación y desarrollo y servicios de consultoría conexos | — |
Official publications
- TED · 00131805-2024 · 4 March 2024
- OJS · 45/2024 · 4 March 2024
Frequently asked questions
- Who is the buyer of this tender?
- The contracting authority is Plectonic LOGIBODY GmbH (European Union).
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